Chemicals and Drugs

Proteoglycan 4

A proteoglycan involved in joint surface lubrication and encoded by the PRG4 gene. Altered expression occurs in some forms of ARTHRITIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A proteoglycan involved in joint surface lubrication and encoded by the PRG4 gene. Altered expression occurs in some forms of ARTHRITIS.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

3 entry terms
  • Lubricating Glycoprotein-I
  • Lubricin
  • PRG4 Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (1985); was LUBRICIN 1985-2025

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.930w.613
  2. D09w.698w.735w.550
  3. D12.776w.395w.650w.613

AMA Style

References

  1. National Library of Medicine. Proteoglycan 4. Medical Subject Headings (MeSH). 2026. Unique ID D000099158. http://id.nlm.nih.gov/mesh/2026/D000099158
  2. Proteoglycan 4. In: Wikidata. https://www.wikidata.org/wiki/Q21133513