Structured Summary
Abstract
A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.
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Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
7 entry terms
- Blood Coagulation Factor II
- Coagulation Factor II
- Differentiation Reversal Factor
- Factor II
- Factor II, Coagulation
- Factor, Differentiation Reversal
- II, Coagulation Factor
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
a blood coag factor; an enzyme precursor
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AMA Style
References
- National Library of Medicine. Prothrombin. Medical Subject Headings (MeSH). 2026. Unique ID D011516. http://id.nlm.nih.gov/mesh/2026/D011516
- Prothrombin. In: Wikidata. https://www.wikidata.org/wiki/Q548692