Chemicals and Drugs

Proto-Oncogene Protein Spi-1

An ETS MOTIF - containing trans-activator that functions in HEMATOPOIESIS. It activates transcription of critical genes by making genomic regions within HETEROCHROMATIN accessible to other key transcription factors.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An ETS MOTIF - containing trans-activator that functions in HEMATOPOIESIS. It activates transcription of critical genes by making genomic regions within HETEROCHROMATIN accessible to other key transcription factors.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • NF-JB Protein
  • NFIL-1betaA Protein
  • NFbetaA Protein
  • PU.1 Protein
  • Pu-1 Protein
  • Transcription Factor PU.1
  • c-Spi-1 Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (1990); use PROTO-ONCOGENE PROTEIN SPI-1 (NM) 1990-2025

MeSH Hierarchy

Tree Numbers

  1. D12.776w.260w.755.375
  2. D12.776w.624.664.700.203
  3. D12.776w.930w.900.475
  4. D12.776w.964w.925w.984.435

AMA Style

References

  1. National Library of Medicine. Proto-Oncogene Protein Spi-1. Medical Subject Headings (MeSH). 2026. Unique ID D000099232. http://id.nlm.nih.gov/mesh/2026/D000099232
  2. Proto-Oncogene Protein Spi-1. In: Wikidata. https://www.wikidata.org/wiki/Q21108730