Structured Summary
Abstract
Protein-serine-threonine kinases that contain PLECKSTRIN HOMOLOGY DOMAINS and are activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. They play a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
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MeSH Record
Synonyms
53 entry terms
- Protein Kinase B
- Protein-Serine-Threonine Kinase (Rac)
- Proto-Oncogene Protein Akt
- Proto-Oncogene Protein RAC
- RAC-PK Protein
- Rac Protein Kinase
- Related to A and C-Protein
- akt Proto-Oncogene Protein
- c-akt Protein
- c-akt Proto-Oncogene Protein
- Akt, Proto-Oncogene Protein
- Protein, akt Proto-Oncogene
- Protein, c-akt Proto-Oncogene
- Proto Oncogene Protein Akt
- Proto Oncogene Protein RAC
- Proto Oncogene Proteins c akt
- Proto-Oncogene Protein, akt
- Proto-Oncogene Protein, c-akt
- RAC PK Protein
- RAC, Proto-Oncogene Protein
- Related to A and C Protein
- akt Proto Oncogene Protein
- c akt Proto Oncogene Protein
- c-akt, Proto-Oncogene Proteins
- AKT1 Protein Kinase
- AKT2 Protein Kinase
- AKT3 Protein Kinase
- Akt-alpha Protein
- Akt-beta Protein
- Akt-gamma Protein
- Protein Kinase B alpha
- Protein Kinase B beta
- Protein Kinase B gamma
- Proto-Oncogene Proteins c-akt1
- Proto-Oncogene Proteins c-akt2
- Proto-Oncogene Proteins c-akt3
- Rac-PK alpha Protein
- Rac-PK beta Protein
- Akt alpha Protein
- Akt beta Protein
- Akt gamma Protein
- Proteins c-akt1, Proto-Oncogene
- Proteins c-akt2, Proto-Oncogene
- Proteins c-akt3, Proto-Oncogene
- Proto Oncogene Proteins c akt1
- Proto Oncogene Proteins c akt2
- Proto Oncogene Proteins c akt3
- Rac PK alpha Protein
- Rac PK beta Protein
- alpha Protein, Rac-PK
- c-akt1, Proto-Oncogene Proteins
- c-akt2, Proto-Oncogene Proteins
- c-akt3, Proto-Oncogene Proteins
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1987)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Proto-Oncogene Proteins c-akt. Medical Subject Headings (MeSH). 2026. Unique ID D051057. http://id.nlm.nih.gov/mesh/2026/D051057
- Proto-Oncogene Proteins c-akt. In: Wikidata. https://www.wikidata.org/wiki/Q21114990