Structured Summary
Abstract
An enzyme that catalyzes the release of a N-terminal pyroglutamyl group from a polypeptide provided the next residue is not proline. It is inhibited by thiol-blocking reagents and occurs in mammalian tissues, microorganisms, and plants. (From Enzyme Nomenclature, 1992) EC 3.4.19.3.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
11 entry terms
- 5-Oxoprolyl-Peptidase
- Pyroglutamate Aminopeptidase
- Pyroglutamyl-Peptide Hydrolase
- Pyrrolidonecarboxylate Peptidase
- Pyrrolidonyl Peptidase
- 5 Oxoprolyl Peptidase
- Aminopeptidase, Pyroglutamate
- Peptidase, Pyrrolidonecarboxylate
- Peptidase, Pyrrolidonyl
- Pyroglutamyl Peptidase I
- Pyroglutamyl Peptide Hydrolase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
95: was 5-OXOPROLYL-PEPTIDASE 1991-94; was PYROGLUTAMATE AMINOPEPTIDASE see under AMINOPEPTIDASES 1975-90
MeSH Record
Previous Indexing
- Aminopeptidases (1970-1974)
- Pyrrolidonecarboxylic Acid (1972-1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Pyroglutamyl-Peptidase I. Medical Subject Headings (MeSH). 2026. Unique ID D011751. http://id.nlm.nih.gov/mesh/2026/D011751
- Pyroglutamyl-Peptidase I. In: Wikidata. https://www.wikidata.org/wiki/Q21174966