Structured Summary
Abstract
A pyruvate dehydrogenase kinase isozyme located in the mitochondria which converts PYRUVATE to ACETYL CoA in the CITRIC ACID CYCLE, phosphorylates SERINE residues on pyruvate dehydrogenase using ATP, and plays a key role in the regulation of GLUCOSE and fatty acid metabolism.
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Broader headings
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Synonyms
8 entry terms
- PDH Kinase
- Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase
- Pyruvate Dehydrogenase (Lipoamide) Kinase
- Pyruvate Dehydrogenase Kinase
- Dehydrogenase Kinase, Pyruvate
- Kinase, PDH
- Kinase, Pyruvate Dehydrogenase
- Pyruvate Dehydrogenase Acetyl Transferring Kinase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2021(1972)
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AMA Style
References
- National Library of Medicine. Pyruvate Dehydrogenase Acetyl-Transferring Kinase. Medical Subject Headings (MeSH). 2026. Unique ID D000081382. http://id.nlm.nih.gov/mesh/2026/D000081382
- Pyruvate Dehydrogenase Acetyl-Transferring Kinase. In: Wikipedia. https://en.wikipedia.org/wiki/Pyruvate_dehydrogenase_kinase
- Pyruvate Dehydrogenase Acetyl-Transferring Kinase. In: Wikidata. https://www.wikidata.org/wiki/Q6321025