Chemicals and Drugs

RNA Precursors

RNA transcripts of the DNA that are in some unfinished stage of post-transcriptional processing (RNA PROCESSING, POST-TRANSCRIPTIONAL) required for function. RNA precursors may undergo several steps of RNA SPLICING during which the phosphodiester bonds at exon-intron boundaries are cleaved and the introns are excised. Consequently a new bond is formed between the ends of the exons. Resulting mature RNAs can then be used; for example, mature mRNA (RNA, MESSENGER) is used as a template for protein production.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

RNA transcripts of the DNA that are in some unfinished stage of post-transcriptional processing (RNA PROCESSING, POST-TRANSCRIPTIONAL) required for function. RNA precursors may undergo several steps of RNA SPLICING during which the phosphodiester bonds at exon-intron boundaries are cleaved and the introns are excised. Consequently a new bond is formed between the ends of the exons. Resulting mature RNAs can then be used; for example, mature mRNA (RNA, MESSENGER) is used as a template for protein production.

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Classification

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Synonyms

31 entry terms
  • Precursors, RNA
  • Pre-mRNA
  • Pre-rRNA
  • Pre-snRNA
  • Pre-tRNA
  • Precursor RNA
  • Primary RNA Transcript
  • Primary Transcript, RNA
  • RNA Precursor
  • RNA, Messenger, Precursors
  • RNA, Ribosomal, Precursors
  • RNA, Small Nuclear, Precursors
  • RNA, Transfer, Precursors
  • mRNA Precursor
  • rRNA Precursor
  • snRNA Precursor
  • tRNA Precursor
  • Pre mRNA
  • Pre rRNA
  • Pre snRNA
  • Pre tRNA
  • Precursor, RNA
  • Precursor, mRNA
  • Precursor, rRNA
  • Precursor, snRNA
  • Precursor, tRNA
  • RNA Primary Transcript
  • RNA Transcript, Primary
  • RNA, Precursor
  • Transcript, Primary RNA
  • Transcript, RNA Primary

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

coordinate with specific RNA

MeSH Record

History Note

88

MeSH Record

Previous Indexing

  • Nucleic Acid Precursors (1975-1987)
  • Nucleic Acids (1966-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. RNA Precursors. Medical Subject Headings (MeSH). 2026. Unique ID D012322. http://id.nlm.nih.gov/mesh/2026/D012322
  2. RNA Precursors. In: Wikidata. https://www.wikidata.org/wiki/Q76693270