Chemicals and Drugs

RNA Probes

RNA, usually prepared by transcription from cloned DNA, which complements a specific mRNA or DNA and is generally used for studies of virus genes, distribution of specific RNA in tissues and cells, integration of viral DNA into genomes, transcription, etc. Whereas DNA PROBES are preferred for use at a more macroscopic level for detection of the presence of DNA/RNA from specific species or subspecies, RNA probes are preferred for genetic studies. Conventional labels for the RNA probe include radioisotope labels 32P and 125I and the chemical label biotin. RNA probes may be further divided by category into plus-sense RNA probes, minus-sense RNA probes, and antisense RNA probes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

RNA, usually prepared by transcription from cloned DNA, which complements a specific mRNA or DNA and is generally used for studies of virus genes, distribution of specific RNA in tissues and cells, integration of viral DNA into genomes, transcription, etc. Whereas DNA PROBES are preferred for use at a more macroscopic level for detection of the presence of DNA/RNA from specific species or subspecies, RNA probes are preferred for genetic studies. Conventional labels for the RNA probe include radioisotope labels 32P and 125I and the chemical label biotin. RNA probes may be further divided by category into plus-sense RNA probes, minus-sense RNA probes, and antisense RNA probes.

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

6 entry terms
  • Gene Probes, RNA
  • RNA Probe
  • Probe, RNA
  • Probes, RNA
  • Probes, RNA Gene
  • RNA Gene Probes

MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

usually no qualif: /drug eff /ultrastruct permitted

MeSH Record

History Note

89

MeSH Record

Previous Indexing

  • Nucleic Acid Hybridization (1972-1988)
  • RNA, Messenger (1972-1988)

MeSH Hierarchy

Tree Numbers

  1. D13.444w.600.723
  2. D27.505.259.750w.600.825
  3. D27.720.470.530w.600.825

AMA Style

References

  1. National Library of Medicine. RNA Probes. Medical Subject Headings (MeSH). 2026. Unique ID D015347. http://id.nlm.nih.gov/mesh/2026/D015347
  2. RNA Probes. In: Wikidata. https://www.wikidata.org/wiki/Q50430204