Chemicals and Drugs

Regulatory Factor X Transcription Factors

A family of eukaryotic transcription factors that recognize and bind to a highly-conserved cis-regulatory sequence (X-box) within the promoter region of MHC CLASS II GENES. They contain a conserved winged-helix DNA binding domain and function as homo or heterodimers.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of eukaryotic transcription factors that recognize and bind to a highly-conserved cis-regulatory sequence (X-box) within the promoter region of MHC CLASS II GENES. They contain a conserved winged-helix DNA binding domain and function as homo or heterodimers.

MeSH Record

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MeSH Record

Synonyms

3 entry terms
  • RFX Transcription Factors
  • Factors, RFX Transcription
  • Transcription Factors, RFX

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1988)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.260w.950w.624
  2. D12.776w.930w.977w.624

AMA Style

References

  1. National Library of Medicine. Regulatory Factor X Transcription Factors. Medical Subject Headings (MeSH). 2026. Unique ID D000071701. http://id.nlm.nih.gov/mesh/2026/D000071701
  2. Regulatory Factor X Transcription Factors. In: Wikidata. https://www.wikidata.org/wiki/Q76931603