Chemicals and Drugs

Remifentanil

A piperidine-propionate derivative and opioid analgesic structurally related to FENTANYL. It functions as a short-acting MU OPIOID RECEPTOR agonist, and is used as an analgesic during induction or maintenance of general anesthesia, following surgery, during childbirth, and in mechanically ventilated patients under intensive care.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A piperidine-propionate derivative and opioid analgesic structurally related to FENTANYL. It functions as a short-acting MU OPIOID RECEPTOR agonist, and is used as an analgesic during induction or maintenance of general anesthesia, following surgery, during childbirth, and in mechanically ventilated patients under intensive care.

Chemical Identity

Chemical Information

Molecular Formula
C20H28N2O5
Molecular Weight
376.4 g/mol
CAS Registry No.
132875-61-7
IUPAC Name
methyl 1-(3-methoxy-3-oxopropyl)-4-(N-propanoylanilino)piperidine-4-carboxylate
InChIKey
ZTVQQQVZCWLTDF-UHFFFAOYSA-N
SMILES
CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC(=O)OC)C(=O)OC
MeSH Unique ID
D000077208
Source
PubChem CID 60815

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

7 entry terms
  • 3-(4-Methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic Acid Methyl Ester
  • GI 87084B
  • GI-87084B
  • GI87084B
  • Remifentanil Hydrochloride
  • Remifentanil Monohydrochloride
  • Ultiva

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1991)

MeSH Hierarchy

Tree Numbers

  1. D02w.241w.081.751.756w
  2. D03w.383.621.828w

AMA Style

References

  1. National Library of Medicine. Remifentanil. Medical Subject Headings (MeSH). 2026. Unique ID D000077208. http://id.nlm.nih.gov/mesh/2026/D000077208
  2. Remifentanil. In: Wikipedia. https://en.wikipedia.org/wiki/Remifentanil
  3. Remifentanil. In: Wikidata. https://www.wikidata.org/wiki/Q417902
  4. Remifentanil. In: PubChem Compound. CID 60815. https://pubchem.ncbi.nlm.nih.gov/compound/60815