Diseases

Renal Tubular Acidosis

A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.

MeSH Record

Classification

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MeSH Record

Synonyms

30 entry terms
  • Acidosis, Renal Tubular
  • Acidosis, Renal Tubular, Type I
  • Acidosis, Renal Tubular, Type II
  • Autosomal Dominant Distal Renal Tubular Acidosis
  • Classic Distal Renal Tubular Acidosis
  • Distal Renal Tubular Acidosis
  • Proximal Renal Tubular Acidosis
  • RTA, Classic Type
  • RTA, Distal Type, Autosomal Dominant
  • RTA, Gradient Type
  • RTA, Proximal Type
  • Renal Tubular Acidosis 1
  • Renal Tubular Acidosis I
  • Renal Tubular Acidosis II
  • Renal Tubular Acidosis, Distal, Autosomal Dominant
  • Renal Tubular Acidosis, Proximal
  • Renal Tubular Acidosis, Proximal, with Ocular Abnormalities
  • Renal Tubular Acidosis, Type I
  • Renal Tubular Acidosis, Type II
  • Type I Renal Tubular Acidosis
  • Type II Renal Tubular Acidosis
  • Classic Type RTA
  • Classic Type RTAs
  • Gradient Type RTA
  • Gradient Type RTAs
  • Proximal Type RTA
  • Proximal Type RTAs
  • RTAs, Classic Type
  • RTAs, Gradient Type
  • RTAs, Proximal Type

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

65

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

WJ 301.5

AMA Style

References

  1. National Library of Medicine. Renal Tubular Acidosis. Medical Subject Headings (MeSH). 2026. Unique ID D000141. http://id.nlm.nih.gov/mesh/2026/D000141
  2. Renal Tubular Acidosis. In: Wikipedia. https://en.wikipedia.org/wiki/Renal_tubular_acidosis
  3. Renal Tubular Acidosis. In: Wikidata. https://www.wikidata.org/wiki/Q1516211