Phenomena and Processes

Replication Origin

A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds bidirectionally or unidirectionally. It contains the sites where the first separation of the complementary strands occurs, a primer RNA is synthesized, and the switch from primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds bidirectionally or unidirectionally. It contains the sites where the first separation of the complementary strands occurs, a primer RNA is synthesized, and the switch from primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

8 entry terms
  • Origin of Replication
  • ori Region
  • Origin, Replication
  • Origins, Replication
  • Region, ori
  • Regions, ori
  • Replication Origins
  • ori Regions

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

95

MeSH Record

Previous Indexing

  • DNA Replication (1969-1994)

MeSH Hierarchy

Tree Numbers

  1. G05.360w.340w.024.220w.760w
  2. G05.360w.340w.024.745w.725w

AMA Style

References

  1. National Library of Medicine. Replication Origin. Medical Subject Headings (MeSH). 2026. Unique ID D018741. http://id.nlm.nih.gov/mesh/2026/D018741
  2. Replication Origin. In: Wikipedia. https://en.wikipedia.org/wiki/Origin_of_replication
  3. Replication Origin. In: Wikidata. https://www.wikidata.org/wiki/Q976651