Chemicals and Drugs

Retinoblastoma-Like Protein p107

A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. It contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. It contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.

MeSH Record

Classification

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MeSH Record

Synonyms

6 entry terms
  • RBL1 Protein
  • Retinoblastoma Like Protein p107
  • Retinoblastoma-Like Protein 1
  • p107 Tumor Suppressor Protein
  • Retinoblastoma Like Protein 1
  • p107, Retinoblastoma-Like Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1991)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Retinoblastoma-Like Protein p107. Medical Subject Headings (MeSH). 2026. Unique ID D050720. http://id.nlm.nih.gov/mesh/2026/D050720
  2. Retinoblastoma-Like Protein p107. In: Wikipedia. https://en.wikipedia.org/wiki/Retinoblastoma-like_protein_1
  3. Retinoblastoma-Like Protein p107. In: Wikidata. https://www.wikidata.org/wiki/Q907420