Structured Summary
Abstract
Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.
MeSH Record
Classification
Related Concepts
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MeSH Record
Synonyms
7 entry terms
- Rb Gene Product
- Rb Protein
- Rb1 Gene Product
- Retinoblastoma Nuclear Phosphoprotein p105-Rb
- p105-Rb Protein
- Retinoblastoma Nuclear Phosphoprotein p105 Rb
- p105 Rb Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
/biosyn /drug eff /physiol /ultrastruct permitted
MeSH Record
History Note
91
MeSH Record
Previous Indexing
- Phosphoproteins (1990)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Retinoblastoma Protein. Medical Subject Headings (MeSH). 2026. Unique ID D016160. http://id.nlm.nih.gov/mesh/2026/D016160
- Retinoblastoma Protein. In: Wikipedia. https://en.wikipedia.org/wiki/Pocket_protein_family
- Retinoblastoma Protein. In: Wikidata. https://www.wikidata.org/wiki/Q24778991