Disciplines and Occupations

Reverse Vaccinology

A process where the genome of a pathogen is studied to find genes that may code for antigen proteins. If found, the putative antigen genes are then cloned, expressed in bacteria, and used to vaccinate experimental animals. If the expressed protein is shown to induce protective immunity it then becomes a candidate for further studies as a vaccine to be used to prevent infection.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A process where the genome of a pathogen is studied to find genes that may code for antigen proteins. If found, the putative antigen genes are then cloned, expressed in bacteria, and used to vaccinate experimental animals. If the expressed protein is shown to induce protective immunity it then becomes a candidate for further studies as a vaccine to be used to prevent infection.

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MeSH Record

Aspects Covered

12 allowable subheadings

Indexed with the subheadings classification, economics, education, ethics, history, instrumentation, legislation & jurisprudence, methods, organization & administration, standards, statistics & numerical data, trends.

MeSH Record

History Note

2026

MeSH Hierarchy

Tree Number

  1. H02w.403w.894.001w

AMA Style

References

  1. National Library of Medicine. Reverse Vaccinology. Medical Subject Headings (MeSH). 2026. Unique ID D000099138. http://id.nlm.nih.gov/mesh/2026/D000099138
  2. Reverse Vaccinology. In: Wikipedia. https://en.wikipedia.org/wiki/Reverse_vaccinology
  3. Reverse Vaccinology. In: Wikidata. https://www.wikidata.org/wiki/Q7318278