Phenomena and Processes

Rh Isoimmunization

The process by which fetal Rh+ erythrocytes enter the circulation of an Rh- mother, causing her to produce IMMUNOGLOBULIN G antibodies, which can cross the placenta and destroy the erythrocytes of Rh+ fetuses. Rh isoimmunization can also be caused by BLOOD TRANSFUSION with mismatched blood.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The process by which fetal Rh+ erythrocytes enter the circulation of an Rh- mother, causing her to produce IMMUNOGLOBULIN G antibodies, which can cross the placenta and destroy the erythrocytes of Rh+ fetuses. Rh isoimmunization can also be caused by BLOOD TRANSFUSION with mismatched blood.

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Classification

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See Also

MeSH Record

Synonyms

11 entry terms
  • Isoimmunization, Rhesus
  • Isoimmunization, Rh
  • Isoimmunizations, Rh
  • Isoimmunizations, Rhesus
  • Rh Isoimmunizations
  • Rhesus Isoimmunization
  • Rhesus Isoimmunizations
  • Rh Sensitization
  • Rh Sensitizations
  • Sensitization, Rh
  • Sensitizations, Rh

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

1985; for RH SENSITIZATION use RH-HR BLOOD GROUP SYSTEM 1980-2009

MeSH Record

Previous Indexing

  • RH-HR Blood-Group System (1966-1984)

MeSH Hierarchy

Tree Numbers

  1. G09.188.114.750w
  2. G12.122.780w
  3. G12.186.750w

MeSH Record

NLM Classification

WH 425

AMA Style

References

  1. National Library of Medicine. Rh Isoimmunization. Medical Subject Headings (MeSH). 2026. Unique ID D012203. http://id.nlm.nih.gov/mesh/2026/D012203
  2. Rh Isoimmunization. In: Wikipedia. https://en.wikipedia.org/wiki/Rh_disease
  3. Rh Isoimmunization. In: Wikidata. https://www.wikidata.org/wiki/Q1712331