Chemicals and Drugs

Ribavirin

A nucleoside antimetabolite antiviral agent that blocks nucleic acid synthesis and is used against both RNA and DNA viruses.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A nucleoside antimetabolite antiviral agent that blocks nucleic acid synthesis and is used against both RNA and DNA viruses.

Chemical Identity

Chemical Information

Molecular Formula
C8H12N4O5
Molecular Weight
244.20 g/mol
CAS Registry No.
36791-04-5
IUPAC Name
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
InChIKey
IWUCXVSUMQZMFG-AFCXAGJDSA-N
SMILES
C1=NC(=NN1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N
MeSH Unique ID
D012254
Source
PubChem CID 37542

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

14 entry terms
  • Ribovirin
  • Tribavirin
  • ICN-1229
  • Rebetol
  • Ribamide
  • Ribamidil
  • Ribamidyl
  • Ribasphere
  • Vilona
  • Viramide
  • Virazide
  • Virazole
  • ICN 1229
  • ICN1229

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(78); was see under RIBONUCLEOSIDES 1978-90; was VIRAZOLE see under RIBONUCLEOSIDES 1975-77; VIRAZOLE was see RIBAVIRIN 1978-91

MeSH Record

Previous Indexing

  • Amides (1966-1974)
  • Nucleosides (1966-1972)
  • Ribonucleosides (1973-1974)
  • Triazoles (1966-1974)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Ribavirin. Medical Subject Headings (MeSH). 2026. Unique ID D012254. http://id.nlm.nih.gov/mesh/2026/D012254
  2. Ribavirin. In: Wikipedia. https://en.wikipedia.org/wiki/Ribavirin
  3. Ribavirin. In: Wikidata. https://www.wikidata.org/wiki/Q421862
  4. Ribavirin. In: PubChem Compound. CID 37542. https://pubchem.ncbi.nlm.nih.gov/compound/37542