Structured Summary
Abstract
A directed change in translational READING FRAMES that allows the production of a single protein from two or more OVERLAPPING GENES. The process is programmed by the nucleotide sequence of the MRNA and is sometimes also affected by the secondary or tertiary mRNA structure. It has been described mainly in VIRUSES (especially RETROVIRUSES); RETROTRANSPOSONS; and bacterial insertion elements but also in some cellular genes.
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Synonyms
13 entry terms
- Frameshifting, Ribosomal
- Frameshifting, Translational
- Ribosomal Frame Shift
- Ribosomal Frame Shifting
- Ribosomal Frameshift
- Frame Shift, Ribosomal
- Frame Shifting, Ribosomal
- Frame Shifts, Ribosomal
- Frameshift, Ribosomal
- Frameshifts, Ribosomal
- Ribosomal Frame Shifts
- Ribosomal Frameshifts
- Translational Frameshifting
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Aspects Covered
6 allowable subheadings
Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.
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Indexing Annotation
do not confuse with FRAMESHIFT MUTATION, non-physiol insertion or deletion of coding sequence nucleotides
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History Note
96; was RIBOSOMAL FRAMESHIFT see FRAMESHIFT MUTATION 1991-95
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Previous Indexing
- Frameshift Mutation (1991-1995)
- Ribosomes (1979-1995)
- Translation, Genetic (1979-1995)
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References
- National Library of Medicine. Ribosomal Frameshifting. Medical Subject Headings (MeSH). 2026. Unique ID D018965. http://id.nlm.nih.gov/mesh/2026/D018965
- Ribosomal Frameshifting. In: Wikidata. https://www.wikidata.org/wiki/Q101830413