Chemicals and Drugs

Rocuronium

An androstanol non-depolarizing neuromuscular blocking agent. It has a mono-quaternary structure and is a weaker nicotinic antagonist than PANCURONIUM.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An androstanol non-depolarizing neuromuscular blocking agent. It has a mono-quaternary structure and is a weaker nicotinic antagonist than PANCURONIUM.

Chemical Identity

Chemical Information

Molecular Formula
C32H53N2O4+
Molecular Weight
529.8 g/mol
CAS Registry No.
143558-00-3
IUPAC Name
[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enylpyrrolidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
InChIKey
YXRDKMPIGHSVRX-OOJCLDBCSA-N
SMILES
CC(=O)O[C@H]1[C@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C@@H]([C@H](C4)O)N5CCOCC5)C)C)[N+]6(CCCC6)CC=C
MeSH Unique ID
D000077123
Source
PubChem CID 441290

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • 1-(17-(Acetoyl)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl)-1-(2-propenyl)pyrrolidinium
  • Androstane-3,17-diol, 2-(4-morpholinyl)-16-(1-(2-propen-1-yl)-1-pyrrolidiniumyl)-, 17-acetate, (2beta,3alpha,5alpha,16beta,17beta)-
  • Esmeron
  • Esmerone
  • ORG 9426
  • ORG-9426
  • Pyrrolidinium, 1-((2beta,3alpha,5alpha,16beta,17beta)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl)-1-(2-propenyl)-, bromide
  • Rocuronium Bromide
  • Zemuron
  • ORG9426

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1989)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.054.040w.783

AMA Style

References

  1. National Library of Medicine. Rocuronium. Medical Subject Headings (MeSH). 2026. Unique ID D000077123. http://id.nlm.nih.gov/mesh/2026/D000077123
  2. Rocuronium. In: Wikidata. https://www.wikidata.org/wiki/Q185331
  3. Rocuronium. In: PubChem Compound. CID 441290. https://pubchem.ncbi.nlm.nih.gov/compound/441290