Chemicals and Drugs

Rolipram

A phosphodiesterase 4 inhibitor with antidepressant properties.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A phosphodiesterase 4 inhibitor with antidepressant properties.

Chemical Identity

Chemical Information

Molecular Formula
C16H21NO3
Molecular Weight
275.34 g/mol
CAS Registry No.
61413-54-5
IUPAC Name
4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one
InChIKey
HJORMJIFDVBMOB-UHFFFAOYSA-N
SMILES
COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3
MeSH Unique ID
D020889
Source
PubChem CID 5092

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • ZK-62711
  • ZK 62711
  • ZK62711

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2000; use ROLIPRAM (NM) 1979-1999

MeSH Record

Previous Indexing

  • Cyclopentanes (1979-1982)
  • Pyrrolidinones (1983-1999)

MeSH Hierarchy

Tree Number

  1. D03w.383.773.812.785w

AMA Style

References

  1. National Library of Medicine. Rolipram. Medical Subject Headings (MeSH). 2026. Unique ID D020889. http://id.nlm.nih.gov/mesh/2026/D020889
  2. Rolipram. In: Wikipedia. https://en.wikipedia.org/wiki/Rolipram
  3. Rolipram. In: Wikidata. https://www.wikidata.org/wiki/Q410285
  4. Rolipram. In: PubChem Compound. CID 5092. https://pubchem.ncbi.nlm.nih.gov/compound/5092