Structured Summary
Abstract
A purine derivative and competitive inhibitor of CYCLIN-DEPENDENT KINASES that has therapeutic potential as an antineoplastic and antiviral agent.
Chemical Identity
Chemical Information
- Molecular Formula
- C19H26N6O
- Molecular Weight
- 354.4 g/mol
- CAS Registry No.
- 186692-46-6
- IUPAC Name
- (2R)-2-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]butan-1-ol
- InChIKey
- BTIHMVBBUGXLCJ-OAHLLOKOSA-N
- SMILES
- CC[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3
- MeSH Unique ID
- D000077546
- Source
- PubChem CID 160355
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- (2R)-2-((6-Benzylamino-9-(propan-2-yl)-9H-purin-2-yl)amino)butan-1-ol
- 2-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine
- CYC 202
- CYC-202
- CYC202
- R-roscovitine
- Seliciclib
- R roscovitine
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (1997)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Roscovitine. Medical Subject Headings (MeSH). 2026. Unique ID D000077546. http://id.nlm.nih.gov/mesh/2026/D000077546
- Roscovitine. In: Wikipedia. https://en.wikipedia.org/wiki/Seliciclib
- Roscovitine. In: Wikidata. https://www.wikidata.org/wiki/Q3494619
- Roscovitine. In: PubChem Compound. CID 160355. https://pubchem.ncbi.nlm.nih.gov/compound/160355