Anatomy

Rough Endoplasmic Reticulum

A type of endoplasmic reticulum (ER) where polyribosomes are present on the cytoplasmic surfaces of the ER membranes. This form of ER is prominent in cells specialized for protein secretion and its principal function is to segregate proteins destined for export or intracellular utilization.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A type of endoplasmic reticulum (ER) where polyribosomes are present on the cytoplasmic surfaces of the ER membranes. This form of ER is prominent in cells specialized for protein secretion and its principal function is to segregate proteins destined for export or intracellular utilization.

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Classification

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Synonyms

7 entry terms
  • Endoplasmic Reticulum, Granular
  • Endoplasmic Reticulum, Rough
  • Granular Endoplasmic Reticulum
  • Rough ER
  • ER, Rough
  • ERs, Rough
  • Rough ERs

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

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Indexing Annotation

ENDOPLASMIC RETICULUM, SMOOTH is also available

MeSH Record

History Note

96

MeSH Record

Previous Indexing

  • Endoplasmic Reticulum (1966-1995)

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References

  1. National Library of Medicine. Rough Endoplasmic Reticulum. Medical Subject Headings (MeSH). 2026. Unique ID D018870. http://id.nlm.nih.gov/mesh/2026/D018870
  2. Rough Endoplasmic Reticulum. In: Wikipedia. https://en.wikipedia.org/wiki/Rough_endoplasmic_reticulum
  3. Rough Endoplasmic Reticulum. In: Wikidata. https://www.wikidata.org/wiki/Q7881690