Structured Summary
Abstract
A member of the S100 PROTEIN FAMILY that regulates INFLAMMATION and the immune response. It recruits LEUKOCYTES, promotes cytokine and chemokine production, and regulates leukocyte adhesion and migration. S100A12 can also function via binding to ADVANCED GLYCOSYLATION END PRODUCT-SPECIFIC RECEPTORS, to stimulate innate immune cells.
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
18 entry terms
- CAAF1 Protein
- Calgranulin C Protein
- EN-RAGE Protein
- ENRAGE Protein
- MRP-6 Protein
- S100 A12 Protein
- S100A12
- A12 Protein, S100
- C Protein, Calgranulin
- EN RAGE Protein
- MRP 6 Protein
- Protein, CAAF1
- Protein, Calgranulin C
- Protein, EN-RAGE
- Protein, ENRAGE
- Protein, MRP-6
- Protein, S100 A12
- Protein, S100A12
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2016 (1994)
MeSH Record
Previous Indexing
- Calcium-Binding Proteins (1994-2002)
- S100 Proteins (2003-2015)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. S100A12 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000067616. http://id.nlm.nih.gov/mesh/2026/D000067616
- S100A12 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21124404