Chemicals and Drugs

S100 Calcium Binding Protein A7

An S100 calcium binding protein that contains two EF HAND MOTIFS and also binds zinc. It is secreted via a non-classical secretory pathway and expressed by KERATINOCYTES and epithelial cells of the tongue. It has antimicrobial and immunomodulatory activities and is highly expressed in the skin of patients with PSORIASIS, as well as in bladder and skin epithelial carcinomas.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An S100 calcium binding protein that contains two EF HAND MOTIFS and also binds zinc. It is secreted via a non-classical secretory pathway and expressed by KERATINOCYTES and epithelial cells of the tongue. It has antimicrobial and immunomodulatory activities and is highly expressed in the skin of patients with PSORIASIS, as well as in bladder and skin epithelial carcinomas.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

4 entry terms
  • Psoriasin
  • S100-A7 Protein
  • S100A7 Protein
  • S100 A7 Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Calcium-Binding Proteins (1994-2017)
  • S100 Proteins (2010-2017)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. S100 Calcium Binding Protein A7. Medical Subject Headings (MeSH). 2026. Unique ID D000075023. http://id.nlm.nih.gov/mesh/2026/D000075023
  2. S100 Calcium Binding Protein A7. In: Wikidata. https://www.wikidata.org/wiki/Q24783754