Structured Summary
Abstract
A component of the SWI-SNF CHROMATIN REMODELING complex that functions as a PROTEIN PHOSPHATASE 1 regulator and to stabilize CHROMATIN at PROMOTER REGIONS. It is important for regulating CELL PROLIFERATION and CELL DIFFERENTIATION. Mutations in the SMARCB1 gene are associated with malignant RHABDOID TUMORS.
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Classification
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Synonyms
7 entry terms
- BAF47 Protein
- BRG1-Associated Factor 47 Protein
- Integrase Interactor 1 Protein
- SNF5 Homolog Protein
- Swi-Snf-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily B Member 1
- BRG1 Associated Factor 47 Protein
- Swi Snf Related Matrix Associated Actin Dependent Regulator Of Chromatin Subfamily B Member 1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- Chromosomal Proteins, Non-Histone (2006-2016)
- DNA-Binding Proteins (2006-2016)
- Transcription Factors (2006-2016)
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Tree Numbers
AMA Style
References
- National Library of Medicine. SMARCB1 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000071796. http://id.nlm.nih.gov/mesh/2026/D000071796
- SMARCB1 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q21097435