Structured Summary
Abstract
A large family of structurally-related transcription factors that were originally discovered based upon their close sequence homology to an HMG-box domain found in SEX-DETERMINING REGION Y PROTEIN. Many SOX transcription factors play important roles in regulating CELL DIFFERENTIATION. The numerous members of this family are organized in several subgroups according to structural identities found within the proteins.
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Classification
Related Concepts
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Synonyms
4 entry terms
- SOX Family of Transcription Factors
- SOX Transcription Factor Family
- SRY (Sex Determining Region Y)-Box Proteins
- Transcription Factors, SOX
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
do not confuse entry term SRY (SEX DETERMINING REGION Y)-BOX PROTEINS with SRY SEX-DETERMINING REGION PROTEIN see SEX-DETERMINING REGION Y PROTEIN
MeSH Record
History Note
2009
MeSH Record
Previous Indexing
- DNA-Binding Proteins (1992-2008)
- HMG Proteins (1992-2008)
- Transcription Factors (1992-2008)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. SOX Transcription Factors. Medical Subject Headings (MeSH). 2026. Unique ID D055747. http://id.nlm.nih.gov/mesh/2026/D055747
- SOX Transcription Factors. In: Wikidata. https://www.wikidata.org/wiki/Q24773867