Structured Summary
Abstract
A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.
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Synonyms
6 entry terms
- Monomethylglycine Dehydrogenase
- Sarcosine N-Demethylase
- Dehydrogenase, Monomethylglycine
- Dehydrogenase, Sarcosine
- N-Demethylase, Sarcosine
- Sarcosine N Demethylase
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1976); use OXIDOREDUCTASES, N-DEMETHYLATING, & SARCOSINE 1976-1979
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References
- National Library of Medicine. Sarcosine Dehydrogenase. Medical Subject Headings (MeSH). 2026. Unique ID D050892. http://id.nlm.nih.gov/mesh/2026/D050892
- Sarcosine Dehydrogenase. In: Wikipedia. https://en.wikipedia.org/wiki/Sarcosine_dehydrogenase
- Sarcosine Dehydrogenase. In: Wikidata. https://www.wikidata.org/wiki/Q3451849