Anatomy

Sciatic Nerve

A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.

MeSH Record

Classification

Broader headings

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See Also

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Synonyms

3 entry terms
  • Nerve, Sciatic
  • Nerves, Sciatic
  • Sciatic Nerves

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings abnormalities, anatomy & histology, blood supply, chemistry, cytology, diagnostic imaging, drug effects, embryology, enzymology, growth & development, immunology, injuries, metabolism, microbiology, parasitology, pathology, physiology, physiopathology, radiation effects, surgery, transplantation, ultrastructure, virology.

MeSH Record

Indexing Annotation

dis = SCIATIC NEUROPATHY (IM); neopl = SCIATIC NEUROPATHY (IM) + PERIPHERAL NERVOUS SYSTEM NEOPLASMS (IM) + histol type of neopl (IM)

MeSH Hierarchy

Tree Number

MeSH Record

NLM Classification

WL 400

AMA Style

References

  1. National Library of Medicine. Sciatic Nerve. Medical Subject Headings (MeSH). 2026. Unique ID D012584. http://id.nlm.nih.gov/mesh/2026/D012584
  2. Sciatic Nerve. In: Wikipedia. https://en.wikipedia.org/wiki/Sciatic_nerve
  3. Sciatic Nerve. In: Wikidata. https://www.wikidata.org/wiki/Q307869