Structured Summary
Abstract
The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
8 entry terms
- Collapsin
- Collapsin-1
- Collapsing Factor
- Sem D
- Sema3A
- Semaphorin 3A
- Semaphorin D
- Collapsin 1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2003; use SEMAPHORIN 3A (NM) 1994-2002
MeSH Record
Previous Indexing
- Glycoproteins (1993-2002)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Semaphorin-3A. Medical Subject Headings (MeSH). 2026. Unique ID D040121. http://id.nlm.nih.gov/mesh/2026/D040121
- Semaphorin-3A. In: Wikidata. https://www.wikidata.org/wiki/Q21122063