Chemicals and Drugs

Serpins

A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.

MeSH Record

Classification

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See Also

MeSH Record

Synonyms

9 entry terms
  • Serpin
  • Serpin Peptidase Inhibitors
  • Serpin Protease Inhibitors
  • Inhibitors, Serpin Peptidase
  • Inhibitors, Serpin Protease
  • Peptidase Inhibitors, Serpin
  • Protease Inhibitors, Serpin
  • Serpin Superfamily
  • Superfamily, Serpin

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

90

MeSH Record

Previous Indexing

  • Enzyme Inhibitors (1968-1978)
  • Protease Inhibitors (1979-1989)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QU 143

AMA Style

References

  1. National Library of Medicine. Serpins. Medical Subject Headings (MeSH). 2026. Unique ID D015843. http://id.nlm.nih.gov/mesh/2026/D015843
  2. Serpins. In: Wikipedia. https://en.wikipedia.org/wiki/Serpin
  3. Serpins. In: Wikidata. https://www.wikidata.org/wiki/Q420068