Chemicals and Drugs

Serrate-Jagged Proteins

Cell surface proteins that consist of multiple extracellular EPIDERMAL GROWTH FACTOR - like repeat sequences (EGF repeats), including calcium-binding EGF repeats. They function as transmembrane ligands for NOTCH RECEPTORS to control CELL DIFFERENTIATION during development.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cell surface proteins that consist of multiple extracellular EPIDERMAL GROWTH FACTOR - like repeat sequences (EGF repeats), including calcium-binding EGF repeats. They function as transmembrane ligands for NOTCH RECEPTORS to control CELL DIFFERENTIATION during development.

MeSH Record

Classification

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MeSH Record

Synonyms

4 entry terms
  • Jagged Proteins
  • Serrate Protein
  • Serrate Proteins
  • Serrate Jagged Proteins

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1991)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.930
  2. D12.776w.157w.125w.797
  3. D12.776w.543w.800
  4. D23.529.930

AMA Style

References

  1. National Library of Medicine. Serrate-Jagged Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D000072099. http://id.nlm.nih.gov/mesh/2026/D000072099
  2. Serrate-Jagged Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q24725574