Diseases

Sertoli-Leydig Cell Tumor

A sex cord-gonadal stromal tumor consists of LEYDIG CELLS; SERTOLI CELLS; and FIBROBLASTS in varying proportions and degree of differentiation. Most such tumors produce ANDROGENS in the Leydig cells, formerly known as androblastoma or arrhenoblastoma. Androblastomas occur in the TESTIS or the OVARY causing precocious masculinization in the males, and defeminization, or virilization (VIRILISM) in the females. In some cases, the Sertoli cells produce ESTROGENS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A sex cord-gonadal stromal tumor consists of LEYDIG CELLS; SERTOLI CELLS; and FIBROBLASTS in varying proportions and degree of differentiation. Most such tumors produce ANDROGENS in the Leydig cells, formerly known as androblastoma or arrhenoblastoma. Androblastomas occur in the TESTIS or the OVARY causing precocious masculinization in the males, and defeminization, or virilization (VIRILISM) in the females. In some cases, the Sertoli cells produce ESTROGENS.

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Classification

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MeSH Record

Synonyms

11 entry terms
  • Androblastoma
  • Arrhenoblastoma
  • Sertoli-Leydig Cell Tumors
  • Androblastomas
  • Arrhenoblastomas
  • Cell Tumor, Sertoli-Leydig
  • Cell Tumors, Sertoli-Leydig
  • Sertoli Leydig Cell Tumor
  • Sertoli Leydig Cell Tumors
  • Tumor, Sertoli-Leydig Cell
  • Tumors, Sertoli-Leydig Cell

MeSH Record

Aspects Covered

38 allowable subheadings

Indexed with the subheadings blood, blood supply, cerebrospinal fluid, chemically induced, chemistry, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, ultrastructure, urine, veterinary, virology.

MeSH Record

Indexing Annotation

coordinate IM with OVARIAN NEOPLASMS or TESTICULAR NEOPLASMS

MeSH Record

History Note

1994; for ARRHENOBLASTOMA use ARRHENOBLASTOMA 1966-1994, use ANDROBLASTOMA 1994-2004; for ANDROBLASTOMA use ANDROBLASTOMA 1994-2004

MeSH Record

Previous Indexing

  • Leydig Cell Tumor (1968-1993)
  • Ovarian Neoplasms (1968-1993)
  • Sertoli Cell Tumor (1968-1993)

MeSH Hierarchy

Tree Numbers

  1. C04w.557.475w.750w.847
  2. C04w.588.322w.455w.648
  3. C04w.588.322w.762.500
  4. C04w.588.945w.440.915.500
  5. C12.050.351.500w.056.630w.705w.648
  6. C12.050.351.937w.418.685w.648
  7. C12.100w.250w.056.630w.705w.648
  8. C12.100w.500w.260.937.500
  9. C12.200.294w.260.937.500
  10. C12.200.758w.409.937.500
  11. C12.900w.418.685w.648
  12. C12.900w.619.937.500
  13. C19w.344w.410w.648
  14. C19w.344w.762.500
  15. C19w.391.630w.705w.648
  16. C19w.391.829w.782.500

AMA Style

References

  1. National Library of Medicine. Sertoli-Leydig Cell Tumor. Medical Subject Headings (MeSH). 2026. Unique ID D018310. http://id.nlm.nih.gov/mesh/2026/D018310
  2. Sertoli-Leydig Cell Tumor. In: Wikidata. https://www.wikidata.org/wiki/Q18555257