Chemicals and Drugs

Sevelamer

A polymeric amine that binds phosphate and is used to treat HYPERPHOSPHATEMIA in patients with kidney disease.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A polymeric amine that binds phosphate and is used to treat HYPERPHOSPHATEMIA in patients with kidney disease.

Chemical Identity

Chemical Information

Molecular Formula
C6H12ClNO
Molecular Weight
149.62 g/mol
CAS Registry No.
1392212-84-8
IUPAC Name
2-(chloromethyl)oxirane;prop-2-en-1-amine
InChIKey
ZNSIZMQNQCNRBW-UHFFFAOYSA-N
SMILES
C=CCN.C1C(O1)CCl
MeSH Unique ID
D000069603
Source
PubChem CID 3085017

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • GT335-012
  • RenaGel
  • Sevelamer Carbonate
  • Sevelamer Hydrochloride
  • Carbonate, Sevelamer
  • GT335 012
  • GT335012
  • Hydrochloride, Sevelamer

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (2000)

MeSH Record

Previous Indexing

  • Epoxy Compounds (2000-2015)
  • Polyethylene (2000-2015)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Sevelamer. Medical Subject Headings (MeSH). 2026. Unique ID D000069603. http://id.nlm.nih.gov/mesh/2026/D000069603
  2. Sevelamer. In: Wikipedia. https://en.wikipedia.org/wiki/Sevelamer
  3. Sevelamer. In: Wikidata. https://www.wikidata.org/wiki/Q904153
  4. Sevelamer. In: PubChem Compound. CID 3085017. https://pubchem.ncbi.nlm.nih.gov/compound/3085017