Structured Summary
Abstract
Group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an X-linked or autosomal recessive defect. Mutations occurring in many different genes cause human Severe Combined Immunodeficiency (SCID).
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Classification
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MeSH Record
Synonyms
25 entry terms
- Immunodeficiency Syndrome, Severe Combined
- Immunodeficiency, Severe Combined
- Immunologic Deficiency, Severe Combined
- Severe Combined Immune Deficiency
- Severe Combined Immunodeficiency Syndrome
- Severe Combined Immunologic Deficiency
- Combined Immunodeficiencies, Severe
- Combined Immunodeficiency, Severe
- Immunodeficiencies, Severe Combined
- Severe Combined Immunodeficiencies
- Bare Lymphocyte Syndrome
- Omenn Syndrome
- Omenn's Syndrome
- Reticuloendotheliosis, Familial
- Bare Lymphocyte Syndromes
- Familial Reticuloendothelioses
- Familial Reticuloendotheliosis
- Lymphocyte Syndrome, Bare
- Lymphocyte Syndromes, Bare
- Omenns Syndrome
- Reticuloendothelioses, Familial
- Syndrome, Bare Lymphocyte
- Syndrome, Omenn
- Syndrome, Omenn's
- Syndromes, Bare Lymphocyte
MeSH Record
Aspects Covered
34 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
MeSH Record
History Note
1992
MeSH Record
Previous Indexing
- Immunologic Deficiency Syndromes (1974-1991)
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NLM Classification
QW 740
AMA Style
References
- National Library of Medicine. Severe Combined Immunodeficiency. Medical Subject Headings (MeSH). 2026. Unique ID D016511. http://id.nlm.nih.gov/mesh/2026/D016511
- Severe Combined Immunodeficiency. In: Wikipedia. https://en.wikipedia.org/wiki/Severe_combined_immunodeficiency
- Severe Combined Immunodeficiency. In: Wikidata. https://www.wikidata.org/wiki/Q1334408