Chemicals and Drugs

Shiga Toxins

A class of toxins that inhibit protein synthesis by blocking the interaction of ribosomal RNA; (RNA, RIBOSOMAL) with PEPTIDE ELONGATION FACTORS. They include SHIGA TOXIN which is produced by SHIGELLA DYSENTERIAE and a variety of shiga-like toxins that are produced by pathologic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A class of toxins that inhibit protein synthesis by blocking the interaction of ribosomal RNA; (RNA, RIBOSOMAL) with PEPTIDE ELONGATION FACTORS. They include SHIGA TOXIN which is produced by SHIGELLA DYSENTERIAE and a variety of shiga-like toxins that are produced by pathologic strains of ESCHERICHIA COLI such as ESCHERICHIA COLI O157.

MeSH Record

Classification

Related Concepts

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Drug Class

Pharmacological Action

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See Also

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Synonyms

19 entry terms
  • Shiga-Like Toxins
  • Vero Cell Cytotoxin
  • Vero Cell Cytotoxins
  • Vero Cytotoxin
  • Vero Cytoxins
  • Vero Toxin
  • Vero Toxins
  • Verotoxin
  • Verotoxins
  • Cell Cytotoxins, Vero
  • Cytotoxin, Vero
  • Cytotoxin, Vero Cell
  • Cytotoxins, Vero Cell
  • Cytoxins, Vero
  • Shiga Like Toxins
  • Toxin, Vero
  • Toxins, Shiga
  • Toxins, Shiga-Like
  • Toxins, Vero

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

SHIGA TOXIN is also available

MeSH Record

History Note

2001; for VERO CYTOTOXIN, VERO CELL CYTOTOXIN, VERO TOXIN & VERO TOXIN use SHIGA-LIKE TOXIN I (NM) 1980-2000

MeSH Record

Previous Indexing

  • Bacterial Toxins (1980-2000)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Shiga Toxins. Medical Subject Headings (MeSH). 2026. Unique ID D022603. http://id.nlm.nih.gov/mesh/2026/D022603
  2. Shiga Toxins. In: Wikipedia. https://en.wikipedia.org/wiki/Shiga_toxin
  3. Shiga Toxins. In: Wikidata. https://www.wikidata.org/wiki/Q424753