Chemicals and Drugs

Sialic Acid Binding Ig-like Lectin 3

A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec subtype and contains a single immunoglobulin C2-set domain. It may play a role in intracellular signaling via its interaction with SHP-1 PROTEIN-TYROSINE PHOSPHATASE and SHP-2 PROTEIN-TYROSINE PHOSPHATASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec subtype and contains a single immunoglobulin C2-set domain. It may play a role in intracellular signaling via its interaction with SHP-1 PROTEIN-TYROSINE PHOSPHATASE and SHP-2 PROTEIN-TYROSINE PHOSPHATASE.

MeSH Record

Classification

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See Also

MeSH Record

Synonyms

8 entry terms
  • Antigens, CD33
  • CD33 Antigen
  • CD33 Antigens
  • Glycoprotein gp67
  • Siglec-3
  • Antigen, CD33
  • Sialic Acid Binding Ig like Lectin 3
  • gp67, Glycoprotein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2013

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Sialic Acid Binding Ig-like Lectin 3. Medical Subject Headings (MeSH). 2026. Unique ID D063268. http://id.nlm.nih.gov/mesh/2026/D063268
  2. Sialic Acid Binding Ig-like Lectin 3. In: Wikipedia. https://en.wikipedia.org/wiki/CD33
  3. Sialic Acid Binding Ig-like Lectin 3. In: Wikidata. https://www.wikidata.org/wiki/Q21114013