Chemicals and Drugs

Sialyl Lewis X Antigen

A sialylated version of Lewis X antigen expressed on cell surfaces. It is a ligand for SELECTINS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A sialylated version of Lewis X antigen expressed on cell surfaces. It is a ligand for SELECTINS.

Chemical Identity

Chemical Information

Molecular Formula
C31H52N2O23
Molecular Weight
820.7 g/mol
CAS Registry No.
98603-84-0
IUPAC Name
(2S,4S,5R,6R)-5-acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3R,4R,5R)-5-acetamido-1,2-dihydroxy-6-oxo-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyhexan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
InChIKey
LAQPKDLYOBZWBT-NYLDSJSYSA-N
SMILES
C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O[C@H]([C@H](C=O)NC(=O)C)[C@@H]([C@@H](CO)O)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O[C@@]3(C[C@@H]([C@H]([C@@H](O3)[C@@H]([C@@H](CO)O)O)NC(=O)C)O)C(=O)O)O)O)O)O
MeSH Unique ID
D000080506
Source
PubChem CID 643990

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

21 entry terms
  • 5-Acetylneuraminyl-(2-3)-Galactosyl-(1-4)-(Fucopyranosyl-(1-3))-N-Acetylglucosamine
  • CD15s Antigen
  • NAG-1,4-F-1,3-GN
  • Neu5Ac-2-3-Gal-1-4-(Fuc-1-3)-GlcNAc
  • NeuAcalpha2-3Galbeta1-4(Fucalpha1-3)GlcNAc-R
  • SLe(x)
  • SLe(x)-OS
  • Sialyl Le(x)
  • Sialyl Lewis X
  • Sialyl Lewis(x) Antigen
  • Sialyl Lewis(x) Tetrasaccharide
  • Sialyl SSEA-1
  • Sialyl Stage-Specific Embryonic Antigen-1
  • Sialyl-Lex
  • Sialylated Lewis X Antigen
  • alpha-Neu5Ac-(2-3)-beta-D-Gal-(1-4)-(alpha-L-Fuc-(1-3))-beta-D-GlcNAc
  • Antigen, CD15s
  • Lewis X, Sialyl
  • Sialyl Lex
  • Sialyl SSEA 1
  • Sialyl Stage Specific Embryonic Antigen 1

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2020 (2008)

MeSH Hierarchy

Tree Numbers

  1. D23.050w.285.050.050.500w
  2. D23.050w.301.264.900.050.500w
  3. D23.050w.301.264.965.500.500w
  4. D23.050w.301.290.544w.059.500w
  5. D23.050w.550w.325.050.500w
  6. D23.050w.705.230.544w.059.500w
  7. D23.101w.100.900.050.500w
  8. D23.101w.140.075.050.500w

AMA Style

References

  1. National Library of Medicine. Sialyl Lewis X Antigen. Medical Subject Headings (MeSH). 2026. Unique ID D000080506. http://id.nlm.nih.gov/mesh/2026/D000080506
  2. Sialyl Lewis X Antigen. In: Wikipedia. https://en.wikipedia.org/wiki/Sialyl-Lewis_X
  3. Sialyl Lewis X Antigen. In: Wikidata. https://www.wikidata.org/wiki/Q3959958
  4. Sialyl Lewis X Antigen. In: PubChem Compound. CID 643990. https://pubchem.ncbi.nlm.nih.gov/compound/643990