Structured Summary
Abstract
An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.
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Classification
Broader headings
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Synonyms
8 entry terms
- Hemoglobin S
- Hemoglobin, Sickle
- Deoxygenated Sickle Hemoglobin
- Deoxyhemoglobin S
- Hemoglobin SS
- Hemoglobin, Deoxygenated Sickle
- SS, Hemoglobin
- Sickle Hemoglobin, Deoxygenated
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
/urine: coord IM with HEMOGLOBINURIA (IM); hemoglobin S disease = ANEMIA, SICKLE CELL
MeSH Record
History Note
77(75); was HEMOGLOBIN S 1973-74 (Prov)
MeSH Record
Previous Indexing
- Hemoglobins, Abnormal (1966-1972)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Sickle Hemoglobin. Medical Subject Headings (MeSH). 2026. Unique ID D006451. http://id.nlm.nih.gov/mesh/2026/D006451
- Sickle Hemoglobin. In: Wikidata. https://www.wikidata.org/wiki/Q76876892