Chemicals and Drugs

Signal Recognition Particle

A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes associated with the rough endoplasmic reticulum. It consists of a 7S RNA and at least six polypeptide subunits (relative molecular masses 9, 14, 19, 54, 68, and 72K).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes associated with the rough endoplasmic reticulum. It consists of a 7S RNA and at least six polypeptide subunits (relative molecular masses 9, 14, 19, 54, 68, and 72K).

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

3 entry terms
  • SRP (Signal Recognition Particle)
  • Particle, Signal Recognition
  • Recognition Particle, Signal

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

94; was SIGNAL RECOGNITION PARTICLE (NM) 1985-93

MeSH Record

Previous Indexing

  • Ribonucleoproteins (1985-1993)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.725w.500w.750.800w
  2. D12.776w.664w.962w.500w.750.800w

AMA Style

References

  1. National Library of Medicine. Signal Recognition Particle. Medical Subject Headings (MeSH). 2026. Unique ID D018271. http://id.nlm.nih.gov/mesh/2026/D018271
  2. Signal Recognition Particle. In: Wikipedia. https://en.wikipedia.org/wiki/Signal_recognition_particle
  3. Signal Recognition Particle. In: Wikidata. https://www.wikidata.org/wiki/Q424665