Simethicone

Structured Summary

Abstract

A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base.

Chemical Identity

Chemical Information

Molecular Formula: C₆H₁₈O₄Si₃
Molecular Weight: 238.46 g/mol
CAS Registry No.: 8050-81-5
IUPAC Name: dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane
InChIKey: AMTWCFIAVKBGOD-UHFFFAOYSA-N
SMILES: CO[Si](C)(C)O[Si](C)(C)C.O=[Si]=O
MeSH Unique ID: D012841
Source: PubChem CID 6433516

MeSH Record

Classification

Broader headings

Dimethylpolysiloxanes

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

1 entry terms

Phazyme 125

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analogs & derivatives, analysis, chemical synthesis, chemistry, classification, economics, history, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity.

MeSH Record

History Note

1991(1975)

MeSH Record

Previous Indexing

Silicones (1972-1974)

MeSH Hierarchy

Tree Numbers

D02 w.756 w.650 w.700 w.150 w.750w
D05.750 w.900 w.850 w.150 w.750w
D25.720 w.900 w.850 w.150 w.750w
J01.637.051.720 w.900 w.850 w.150 w.750w

AMA Style

References

National Library of Medicine. Simethicone. Medical Subject Headings (MeSH). 2026. Unique ID D012841. http://id.nlm.nih.gov/mesh/2026/D012841
Simethicone. In: Wikipedia. https://en.wikipedia.org/wiki/Simeticone
Simethicone. In: Wikidata. https://www.wikidata.org/wiki/Q419415
Simethicone. In: PubChem Compound. CID 6433516. https://pubchem.ncbi.nlm.nih.gov/compound/6433516