Chemicals and Drugs

Sodium-Hydrogen Exchangers

A family of plasma membrane exchange glycoprotein antiporters that transport sodium ions and protons across lipid bilayers. They have critical functions in intracellular pH regulation, cell volume regulation, and cellular response to many different hormones and mitogens.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of plasma membrane exchange glycoprotein antiporters that transport sodium ions and protons across lipid bilayers. They have critical functions in intracellular pH regulation, cell volume regulation, and cellular response to many different hormones and mitogens.

MeSH Record

Classification

Broader headings

Narrower headings

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MeSH Record

Synonyms

30 entry terms
  • Na(+)-H(+)-Antiporter
  • Na(+)-H(+)-Antiporters
  • Na(+)-H(+)-Exchanger
  • Na(+)-H(+)-Exchangers
  • SLC9 Na(+)-H(+) Exchangers
  • SLC9 Protein Family
  • SLC9 Proteins
  • SLC9-NHE Protein Family
  • Sodium-Hydrogen Antiporter
  • Sodium-Hydrogen Antiporters
  • Sodium-Hydrogen Exchanger
  • Sodium-Proton Antiporter
  • Sodium-Proton Antiporters
  • Solute Carrier 9 Protein Family
  • Solute Carrier 9 Proteins
  • Antiporter, Sodium-Hydrogen
  • Antiporter, Sodium-Proton
  • Antiporters, Sodium-Hydrogen
  • Antiporters, Sodium-Proton
  • Exchanger, Sodium-Hydrogen
  • Exchangers, Sodium-Hydrogen
  • Protein Family, SLC9
  • Protein Family, SLC9-NHE
  • SLC9 NHE Protein Family
  • Sodium Hydrogen Antiporter
  • Sodium Hydrogen Antiporters
  • Sodium Hydrogen Exchanger
  • Sodium Hydrogen Exchangers
  • Sodium Proton Antiporter
  • Sodium Proton Antiporters

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018 (1994); was SODIUM-HYDROGEN ANTIPORTER (NM) 1980-2017

MeSH Record

Previous Indexing

  • Biological Transport, Active (1976-1982)
  • Carrier Proteins (1980-1993)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.450w.162w.775w
  2. D12.776w.157w.530w.937w.703w
  3. D12.776w.543w.550w.190w.775w
  4. D12.776w.543w.585w.450w.162w.775w
  5. D12.776w.543w.585w.937w.828w

AMA Style

References

  1. National Library of Medicine. Sodium-Hydrogen Exchangers. Medical Subject Headings (MeSH). 2026. Unique ID D017923. http://id.nlm.nih.gov/mesh/2026/D017923
  2. Sodium-Hydrogen Exchangers. In: Wikipedia. https://en.wikipedia.org/wiki/Sodium%E2%80%93hydrogen_antiporter
  3. Sodium-Hydrogen Exchangers. In: Wikidata. https://www.wikidata.org/wiki/Q7553395