Chemicals and Drugs

Solute Carrier Family 12

Inorganic cation-chloride cotransporters mediating the movement of inorganic SODIUM and/or POTASSIUM cations, coupled to the movement of CHLORIDE anions. The solute carrier 12 (SLC12) family can be divided into Na+-dependent SLC12A1-A3 (NKCC1, NKCC2, and NCC) and Na+-independent SLC12A4-A7 (KCC1-KCC4).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Inorganic cation-chloride cotransporters mediating the movement of inorganic SODIUM and/or POTASSIUM cations, coupled to the movement of CHLORIDE anions. The solute carrier 12 (SLC12) family can be divided into Na+-dependent SLC12A1-A3 (NKCC1, NKCC2, and NCC) and Na+-independent SLC12A4-A7 (KCC1-KCC4).

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1 entry terms
  • SLC12A Transporters

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History Note

2024

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Tree Numbers

  1. D12.776w.157w.530w.450w.250.910w
  2. D12.776w.157w.530w.450w.625w.875w
  3. D12.776w.543w.585w.450w.250.918w
  4. D12.776w.543w.585w.450w.625w.875w

AMA Style

References

  1. National Library of Medicine. Solute Carrier Family 12. Medical Subject Headings (MeSH). 2026. Unique ID D000096925. http://id.nlm.nih.gov/mesh/2026/D000096925
  2. Solute Carrier Family 12. In: Wikipedia. https://en.wikipedia.org/wiki/Electroneutral_cation-Cl
  3. Solute Carrier Family 12. In: Wikidata. https://www.wikidata.org/wiki/Q5358207