Chemicals and Drugs

Solute Carrier Organic Anion Transporter Family Member 1B3

A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • Liver-Specific Organic Anion Transporter-2
  • OATP1B3 Protein
  • OATP8 Protein
  • SLC21A8 Protein
  • SLCO1B3 Protein
  • Solute Carrier Family 21 Member 8 Protein
  • Liver Specific Organic Anion Transporter 2

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Organic Anion Transporters, Sodium-Independent (2002-2017)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.450w.074.500w.781.875
  2. D12.776w.157w.530w.937w.905
  3. D12.776w.543w.585w.450w.074.500w.875.875
  4. D12.776w.543w.585w.937w.950

AMA Style

References

  1. National Library of Medicine. Solute Carrier Organic Anion Transporter Family Member 1B3. Medical Subject Headings (MeSH). 2026. Unique ID D000074542. http://id.nlm.nih.gov/mesh/2026/D000074542
  2. Solute Carrier Organic Anion Transporter Family Member 1B3. In: Wikidata. https://www.wikidata.org/wiki/Q21125248