Chemicals and Drugs

Sparteine

A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype.

Chemical Identity

Chemical Information

Molecular Formula
C15H26N2
Molecular Weight
234.38 g/mol
CAS Registry No.
90-39-1
IUPAC Name
(1S,2R,9S,10S)-7,15-diazatetracyclo[7.7.1.02,7.010,15]heptadecane
InChIKey
SLRCCWJSBJZJBV-ZQDZILKHSA-N
SMILES
C1CCN2C[C@@H]3C[C@H]([C@H]2C1)CN4[C@H]3CCCC4
MeSH Unique ID
D013034
Source
PubChem CID 644020

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

31 entry terms
  • 7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-
  • L-Sparteine
  • Lupinidin
  • Lupinidine
  • Sparteine, (-)-Isomer
  • Sparteine, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
  • D-sparteine
  • Depasan Retard
  • Genisteine Alkaloid
  • Pachycarpine
  • Pachycarpine Sulfate (1:1), Pentahydrate, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
  • Sparteine Hydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
  • Sparteine Hydrochloride, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
  • Sparteine Hydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
  • Sparteine Monohydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
  • Sparteine Monohydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
  • Sparteine Sulfate
  • Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer
  • Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
  • Sparteine Sulfate Anhydrous
  • Sparteine, (+)-Isomer
  • Sparteine, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
  • Sparteine, (7R-(7alpha,7abeta,14alpha,14abeta))-Isomer
  • Sparteine, (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer
  • Sparteine, (7S-(7alpha,7abeta,14alpha,14abeta))-Isomer
  • alpha-Isosparteine
  • beta-Isosparteine
  • Anhydrous, Sparteine Sulfate
  • Sulfate Anhydrous, Sparteine
  • alpha Isosparteine
  • beta Isosparteine

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

1963; for PACHYCARPINE use SPARTEINE(NM) 1973-2001

MeSH Hierarchy

Tree Number

  1. D03w.132w.722w.750w

AMA Style

References

  1. National Library of Medicine. Sparteine. Medical Subject Headings (MeSH). 2026. Unique ID D013034. http://id.nlm.nih.gov/mesh/2026/D013034
  2. Sparteine. In: Wikipedia. https://en.wikipedia.org/wiki/Sparteine
  3. Sparteine. In: Wikidata. https://www.wikidata.org/wiki/Q419552
  4. Sparteine. In: PubChem Compound. CID 644020. https://pubchem.ncbi.nlm.nih.gov/compound/644020