Chemicals and Drugs

Spectrin

A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein contains no lipids or carbohydrates, is the predominant species of peripheral erythrocyte membrane proteins, and exists as a fibrous coating on the inner, cytoplasmic surface of the membrane.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein contains no lipids or carbohydrates, is the predominant species of peripheral erythrocyte membrane proteins, and exists as a fibrous coating on the inner, cytoplasmic surface of the membrane.

MeSH Record

Classification

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

11 entry terms
  • Brain beta Spectrin
  • Fodrin
  • Non-Erythroid Beta Spectrin
  • alpha, gamma Brain Spectrin
  • alpha-Fodrin
  • alpha-Spectrin
  • beta-Fodrin
  • beta-Spectrin
  • beta1 sigma1-Spectrin
  • alpha Spectrin
  • beta Spectrin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (1977); was see under MEMBRANE PROTEINS 1978-83, was see under BLOOD PROTEINS 1977

MeSH Record

Previous Indexing

  • Blood Proteins (1966-1976)
  • Cell Membrane (1966-1975)
  • Erythrocytes (1966-1975)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Spectrin. Medical Subject Headings (MeSH). 2026. Unique ID D013049. http://id.nlm.nih.gov/mesh/2026/D013049
  2. Spectrin. In: Wikipedia. https://en.wikipedia.org/wiki/Spectrin
  3. Spectrin. In: Wikidata. https://www.wikidata.org/wiki/Q420870