Structured Summary
Abstract
A group of recessive inherited diseases that feature progressive muscular atrophy and hypotonia. They are classified as type I (Werdnig-Hoffman disease), type II (intermediate form), and type III (Kugelberg-Welander disease). Type I is fatal in infancy, type II has a late infantile onset and is associated with survival into the second or third decade. Type III has its onset in childhood, and is slowly progressive. (J Med Genet 1996 Apr:33(4):281-3)
MeSH Record
Classification
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
MeSH Record
Synonyms
35 entry terms
- Infantile Spinal Muscular Atrophy
- Juvenile Spinal Muscular Atrophy
- Kugelberg-Welander Disease
- Kugelberg-Welander Syndrome
- Muscular Atrophy, Infantile
- Muscular Atrophy, Juvenile
- Muscular Atrophy, Spinal, Infantile
- Muscular Atrophy, Spinal, Infantile Chronic Form
- Muscular Atrophy, Spinal, Intermediate Type
- Muscular Atrophy, Spinal, Type I
- Muscular Atrophy, Spinal, Type II
- Muscular Atrophy, Spinal, Type III
- SMA, Infantile Acute Form
- Spinal Muscular Atrophy 1
- Spinal Muscular Atrophy Type 2
- Spinal Muscular Atrophy Type I
- Spinal Muscular Atrophy Type II
- Spinal Muscular Atrophy Type III
- Spinal Muscular Atrophy, Infantile
- Spinal Muscular Atrophy, Juvenile
- Spinal Muscular Atrophy, Mild Childhood and Adolescent Form
- Spinal Muscular Atrophy, Type 3
- Spinal Muscular Atrophy, Type I
- Spinal Muscular Atrophy, Type II
- Spinal Muscular Atrophy, Type III
- Type I Spinal Muscular Atrophy
- Type II Spinal Muscular Atrophy
- Type III Spinal Muscular Atrophy
- Werdnig Hoffman Disease
- Werdnig-Hoffmann Disease
- Infantile Muscular Atrophy
- Juvenile Muscular Atrophy
- Kugelberg Welander Disease
- Kugelberg Welander Syndrome
- Werdnig Hoffmann Disease
MeSH Record
Aspects Covered
34 allowable subheadings
Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.
MeSH Record
Indexing Annotation
infantile, childhood or adolescent: for other, MUSCULAR ATROPHY, SPINAL is available
MeSH Record
History Note
2000(1988)
MeSH Record
Previous Indexing
- Muscular Atrophy (1966-1987)
- Spinal Cord Diseases (1966-1987)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
WS 340.5
AMA Style
References
- National Library of Medicine. Spinal Muscular Atrophies of Childhood. Medical Subject Headings (MeSH). 2026. Unique ID D014897. http://id.nlm.nih.gov/mesh/2026/D014897
- Spinal Muscular Atrophies of Childhood. In: Wikidata. https://www.wikidata.org/wiki/Q18554312