Chemicals and Drugs

Spliced Leader RNA

The small RNAs which provide spliced leader sequences, SL1, SL2, SL3, SL4 and SL5 (short sequences which are joined to the 5' ends of pre-mRNAs by TRANS-SPLICING). They are found primarily in primitive eukaryotes (protozoans and nematodes).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The small RNAs which provide spliced leader sequences, SL1, SL2, SL3, SL4 and SL5 (short sequences which are joined to the 5' ends of pre-mRNAs by TRANS-SPLICING). They are found primarily in primitive eukaryotes (protozoans and nematodes).

MeSH Record

Classification

Broader headings

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See Also

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Synonyms

22 entry terms
  • RNA, Spliced Leader
  • SL RNA
  • Leader RNA, Spliced
  • SL1 Sequence
  • SL2 Sequence
  • SL3 Sequence
  • SL4 Sequence
  • SL5 Sequence
  • Spliced Leader
  • Spliced Leader Sequences
  • Trans-Spliced Leader Sequences
  • Leader Sequences, Spliced
  • Leader Sequences, Trans-Spliced
  • Leader, Spliced
  • Sequence, SL1
  • Sequence, SL2
  • Sequence, SL3
  • Sequence, SL4
  • Sequence, SL5
  • Sequences, Spliced Leader
  • Sequences, Trans-Spliced Leader
  • Trans Spliced Leader Sequences

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with LEADER SEQUENCES, MRNA see 5' UNTRANSLATED REGION

MeSH Record

History Note

1999

MeSH Record

Previous Indexing

  • RNA, Messenger (1983-1995)
  • Signal Peptides (1987-1998)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Spliced Leader RNA. Medical Subject Headings (MeSH). 2026. Unique ID D020038. http://id.nlm.nih.gov/mesh/2026/D020038
  2. Spliced Leader RNA. In: Wikidata. https://www.wikidata.org/wiki/Q78192533