Chemicals and Drugs

Sterigmatocystin

A carcinogenic mycotoxin produced in high yields by strains of the common molds, Aspergillus versicolor, A. nidulans, and an unidentified species of Bipolaris. It causes necrosis of the liver and kidney and has an inhibitory effect on orotic acid incorporation into nuclear RNA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A carcinogenic mycotoxin produced in high yields by strains of the common molds, Aspergillus versicolor, A. nidulans, and an unidentified species of Bipolaris. It causes necrosis of the liver and kidney and has an inhibitory effect on orotic acid incorporation into nuclear RNA.

Chemical Identity

Chemical Information

Molecular Formula
C18H12O6
Molecular Weight
324.3 g/mol
CAS Registry No.
10048-13-2
IUPAC Name
(3S,7R)-15-hydroxy-11-methoxy-6,8,20-trioxapentacyclo[10.8.0.02,9.03,7.014,19]icosa-1,4,9,11,14,16,18-heptaen-13-one
InChIKey
UTSVPXMQSFGQTM-DCXZOGHSSA-N
SMILES
COC1=C2C(=C3[C@@H]4C=CO[C@@H]4OC3=C1)OC5=CC=CC(=C5C2=O)O
MeSH Unique ID
D013241
Source
PubChem CID 5280389

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/antag permitted but consider also ANTITOXINS;

MeSH Record

History Note

91(75); was see under XANTHENES 1975-90

MeSH Record

Previous Indexing

  • Furans (1973-1974)
  • Xanthenes (1969-1974)

MeSH Hierarchy

Tree Numbers

  1. D03w.633.300.953.852.777w
  2. D23.946w.587w.850w

AMA Style

References

  1. National Library of Medicine. Sterigmatocystin. Medical Subject Headings (MeSH). 2026. Unique ID D013241. http://id.nlm.nih.gov/mesh/2026/D013241
  2. Sterigmatocystin. In: Wikipedia. https://en.wikipedia.org/wiki/Sterigmatocystin
  3. Sterigmatocystin. In: Wikidata. https://www.wikidata.org/wiki/Q2777979
  4. Sterigmatocystin. In: PubChem Compound. CID 5280389. https://pubchem.ncbi.nlm.nih.gov/compound/5280389