Chemicals and Drugs

Streptomycin

An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.

Chemical Identity

Chemical Information

Molecular Formula
C21H39N7O12
Molecular Weight
581.6 g/mol
CAS Registry No.
57-92-1
IUPAC Name
2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine
InChIKey
UCSJYZPVAKXKNQ-HZYVHMACSA-N
SMILES
C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(C=O)O
MeSH Unique ID
D013307
Source
PubChem CID 19649

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

12 entry terms
  • Estreptomicina CEPA
  • Estreptomicina Clariana
  • Estreptomicina Normon
  • Strepto-Fatol
  • Strepto-Hefa
  • Streptomycin Grünenthal
  • Streptomycin Sulfate
  • Streptomycin Sulfate (2:3) Salt
  • Streptomycin Sulphate
  • Streptomycine Panpharma
  • Strepto Fatol
  • Strepto Hefa

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

/adv eff-pois-tox was STREPTOMYCIN TOXICOLOGY 1963-65

MeSH Hierarchy

Tree Number

  1. D09w.408w.051.885w

MeSH Record

NLM Classification

QV 356

AMA Style

References

  1. National Library of Medicine. Streptomycin. Medical Subject Headings (MeSH). 2026. Unique ID D013307. http://id.nlm.nih.gov/mesh/2026/D013307
  2. Streptomycin. In: Wikipedia. https://en.wikipedia.org/wiki/Streptomycin
  3. Streptomycin. In: Wikidata. https://www.wikidata.org/wiki/Q192717
  4. Streptomycin. In: PubChem Compound. CID 19649. https://pubchem.ncbi.nlm.nih.gov/compound/19649