Chemicals and Drugs

Streptozocin

An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.

Chemical Identity

Chemical Information

Molecular Formula
C8H15N3O7
Molecular Weight
265.22 g/mol
CAS Registry No.
18883-66-4
IUPAC Name
1-methyl-1-nitroso-3-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
InChIKey
ZSJLQEPLLKMAKR-GKHCUFPYSA-N
SMILES
CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O
MeSH Unique ID
D013311
Source
PubChem CID 29327

MeSH Record

Classification

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

4 entry terms
  • 2-Deoxy-2-((methylnitrosoamino)carbonyl)amino-D-glucose
  • Streptozotocin
  • Streptozotocine
  • Zanosar

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

93; was STREPTOZOTOCIN 1972-92 (Prov 1972); STREPTOZOCIN was see STREPTOZOTOCIN 1977-92

MeSH Record

Previous Indexing

  • Antibiotics (1966-1971)
  • Nitroso Compounds (1966-1971)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Streptozocin. Medical Subject Headings (MeSH). 2026. Unique ID D013311. http://id.nlm.nih.gov/mesh/2026/D013311
  2. Streptozocin. In: Wikipedia. https://en.wikipedia.org/wiki/Streptozotocin
  3. Streptozocin. In: Wikidata. https://www.wikidata.org/wiki/Q257331
  4. Streptozocin. In: PubChem Compound. CID 29327. https://pubchem.ncbi.nlm.nih.gov/compound/29327